News

Serpin Pharma Secures $2 Million NCI Grant for Innovative Neuropathy Treatment

Serpin Pharma, a Virginia-based biopharmaceutical company, is proud to announce that it has been awarded a $2 million Phase II Small Business Innovation Research (SBIR) grant from the National Cancer Institute (NCI).

This grant will support the clinical development of SP16-3M, a groundbreaking peptide drug designed to prevent chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients.

Collaborative Clinical Trial

The funding will facilitate a collaborative clinical trial led by Dr. Patrick Dillon at the University of Virginia. The trial aims to evaluate the efficacy of SP16-3M in:

– Protecting nerves from chemotherapy-induced toxicity

– Facilitating nerve repair

– Alleviating pain for breast cancer patients undergoing treatment

Addressing a Critical Need

CIPN is a common and often debilitating side effect of cancer treatment that can significantly impact patients’ quality of life. SP163M represents a potential breakthrough in managing this condition. By preventing neuropathy, SP163M could enable patients to complete their full chemotherapy regimens without dose reductions, potentially improving overall cancer treatment outcomes.

Expert Insights

Dr. Patrick Dillon expressed his enthusiasm for the collaboration: “I am excited about this partnership, as both UVA and Serpin are dedicated to finding solutions for treatment-induced neuropathy in cancer patients.”

Dr. Cohava Gelber, Founder and CEO of Serpin Pharma, also shared her thoughts: “We are thrilled to work with Dr. Dillon and UVA to bring the promise of our groundbreaking drug to breast cancer patients, aiming to prevent their suffering from debilitating pain after chemotherapy.”

Looking Ahead
The NCI award highlights the significant potential of SP163M in addressing a critical unmet need in cancer care. As Serpin Pharma advances its clinical development efforts, breast cancer patients may soon have access to this innovative therapy, enhancing their quality of life during and after chemotherapy.

 

Learn more here.

Recent News

02/20/2025

Council on State Biotechnology Associations says NIH funds are a critical component of innovation ecosystem

“Today, the US biotech industry employs nearly 2.3 million people across the US and is making positive contributions to economic impact and national security across all 50 states. In fact, for every dollar the National Institutes of Health (NIH) contributes to a successful drug, the private sector invests over $65, underscoring the agency’s unparalleled return

02/11/2025

Oragenics, Inc. Announces Partnership with BRAINBox Solutions to Revolutionize Concussion Diagnosis and Treatment

Oragenics, Inc. (NYSE American: OGEN), a biotechnology company advancing innovative treatments for concussion and brain-related health conditions,  announced a strategic partnership with BRAINBox Solutions, a leader in multi-modality diagnostics for traumatic brain injury (TBI). This collaboration seeks to develop the first intranasal therapy for mild traumatic brain injury (mTBI) aka concussion, creating a comprehensive trigger-to-treat

02/11/2025

Children’s National and Compremium partner on pediatric medtech innovation

Children’s National Hospital announced a new collaboration with Swiss medical device company Compremium AG to co-develop and commercialize innovative medical technologies designed specifically for pediatric patients. This first-of-its-kind agreement leverages the expertise of Children’s National in pediatric healthcare innovation and Compremium’s non-invasive platform technology for diagnosing pressure-related conditions, accelerating advancements in pediatric medicine. Diagnosing pressure-related